Participates in the innate immune response to microbial agents.
Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Highly Purified
Purity:Purified by Ion Exchange chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human TLR1.
Isotype:IgG
Calc Applications Abbrev:IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 17aa from near the center of human TLR1 (KLH).