The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain.
The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family.
SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling.
Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Applications:Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlImmunoprecipitation: 3-5ng labels 1e6 cellsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
Specificity:Recognizes human SOCS4.
Isotype:IgG
Calc Applications Abbrev:IHC IP WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to human SOCS4 at C-terminal (KLH).