84-1208-67　［取扱停止］RNF34, NT (E3 Ubiquitin-protein Ligase RNF34, Caspase Regulator CARP1, Caspases-8 and -10-associated RING Finger Protein 1, CARP-1, FYVE-RING Finger Protein Momo, Human RING Finger Homologous to Inhibitor of Apoptosis Protein, hRFI, RING Finger Protein 34, RING Finger Protein RIFF) 50ug　R2031-88E

特徴

• Ring Finger homologous to Inhibitor of apoptosis protein (hRFI), an anti-apoptotic protein which has been shown to be a novel modulator of NF-kB activation, leading to the upregulation of Bcl2 and BclXL.
• It is also thought to possess E3 ubiquitin protein ligase activity and has been shown to target caspases 8 and 10 for proteasomal degradation.
• hRFI is expressed ubiquitously, and has been localized to both the nucleus and the cytoplasm.
• hRFI is also expressed in oesophageal, gastric and colorectal cancers, suggesting a possible association between hRFI and the development of digestive tract cancers.
• Applications:Suitable for use in ELISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:32,000Immunohistochemistry (Formalin-fixed, paraffin-embedded): 3.75ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.