PTP gamma, a R5 receptor protein tyrosine phosphatase, has been implicated as a potential tumor suppressor gene in kidney, lung, ovary and breast cancers.
PTP gamma maps to a region of human chromosome 3, 3p21, that is frequently deleted in renal cell carcinoma and lung carcinoma.
PTP gamma expression has been shown to be reduced in breast and lung cancer cell lines and the expression in breast cancer is regulated by 17 beta-estradiol (E2) and Zeranol.
Four protein isoforms of PTP gamma have been documented in rats.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human PTPRG.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa765-782 of human PTPRG (KLH).
