Prostaglandin E Receptor EP3 is a member of the G protein coupled receptor family.
This protein is one of four receptors identified for prostaglandins E2 (PGE2).
This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities.
Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli.
Prostaglandin E2 Receptor EP3 expression has been documented throughout the periphery, especially kidney.
ESTs have been isolated primarily from kidney libraries.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human PTGER. Species sequence homology: Mouse and rat (28/39%).
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to 3rd cytoplasmic domain of human PTGER3 (KLH).
