Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases.
Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens.
Competes with NCOA1 for modulation of ER transcriptional activity.
Probably involved in regulating mitochondrial respiration activity and in aging.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes mouse PHB2. Species sequence homology: human
Isotype：IgG
Calc Applications Abbrev：IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Recombinant corresponding to mouse PHB2 at C-terminal.
