Cytoplasmic anchor protein in p53-associated protein complex.
Regulates the subcellular localization of p53 and subsequent function.
Seems to be part of an atypical cullin-RING-based E3 ubiquitin-protein ligase complex.
In vitro, complexes of CUL9/PARC with either CUL7 or TP53 contain E3 ubiquitin-protein ligase activity.
Applications:Suitable for use in Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:10,000Western Blot: 1:500-1:1000Immunohistochemistry (Formalin fixed paraffin embedded): 1:500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Serum
Purity:Serum
Form:Supplied as a liquid.
Specificity:Recognizes human CUL9.
Isotype:IgG
Calc Applications Abbrev:E IHC IP WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa2503-2517 of human CUL9 at C-terminal (KLH).