MINK1 and MINK2 are serine/threonine protein kinases of the STE subfamily that may play a role in the response to environmental stress.
They appears to act upstream of the JUN N-terminal pathway and may play a role in the development of the brain.
Expression appears to be ubiquitous, highly expressed in the brain, moderately expressed in kidney and spleen, with lower levels present in heart and skeletal muscle.
These proteins are up-regulated during post-natal brain development.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human MINK1. Species sequence homology: Mouse (22/33%).
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to internal domain of human MINK1 (KLH).