Associates with IFNAR1 to form the type I interferon receptor.
Receptor for interferons alpha and beta.
Involved in IFN-mediated STAT1, STAT2 and STAT3 activation.
Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1.
Isoform 3 is a potent inhibitor of type I IFN receptor activity.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity：Recognizes human IFNAR2.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to SYDSPDYTDESCT from the internal region of human IFNAR2.
