Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes.
The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA.
It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue.
The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues.
However, its exact significance is still obscure.
Applications:Suitable for use in ELISA, Immunoprecipitation, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:10,000-1:20,000Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:goat
Source Antibody:human
Grade:Purified
Purity:Purified
Form:Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human AHSG.
Isotype:IgG
Calc Applications Abbrev:E IHC IP WB
Calc Crossreactivity:Hu
Immunogen:Recombinant corresponding to human fetuin (a2-HS glycoprotein) processed to remove a 40aa residue bridging peptide resulting in the mature form of the protein.