FANCG, involved in Fanconi anemia, confers resistance to both hygromycin and mitomycin C.
FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes.
The putative 622aa protein has a leucine-zipper motif at its N-terminus.
Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies.
A minimum of 8 FA genes have been identified.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.5-1ug/mlImmunohistochemistry (Formalin-fixed, paraffin-embedded): 3ug/mlOptimal dilutions to be determined by the researcher
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human FANCG
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide LEEFRTSLPKSCDL from the C-terminal of human FANCG.