The poliovirus receptor (PVR) is a transmembrane glycoprotein belonging to the immunoglobulin superfamily.
PVR is involved in intercellular adhesion and its cytoplasmic domain may target endocytic vesicles to the microtubular network.
The extracellular domain of PVR mediates cell attachment to the extracellular matrix molecule vitronectin, while its cytoplasmic domain interacts with the dynein light chain Tctex-1.
PVR is a primate-restricted protein expressed during development in mesenchymal tissues and ventrally derived structures within the CNS.
Its exact biological function remains to be determined; it is reported that PVR is aberrantly expressed in tumors of neuroectodermal origin.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human PVR.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa403-417 of human PVR (KLH).
