Catenins are proteins associated with complexes that contain cadherin cell adhesion molecules.
Delta-1-catenin is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development.
It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state.
Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins.
These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion.
While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin-fixed, paraffin-embedded): 1:15 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in10mM PBS, pH 7.4, BSA, sodium azide.
Specificity：Recognizes human P120.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the C-terminal of human P120.
