84-1196-37　Ankyrin G (Ankyrin-3, Node of Ranvier, Ankyrin G119, Ankyrin 3, FLJ45464, RP11-369L1.1, Node of Ranvier [ankyrin G], ANK3) 100ug　A2295-18A

特徴

• Ankyrin G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier.
• Ankyrin G is also found at sites of epithelial cell- cell contact and in the intracellular membranes of some cells.
• Ankyrin G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain.
• Ankyrin G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.
• Applications:Suitable for use in ELISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:16,000Western Blot: 3-5ug/ml.
• Testing in paraffin-embedded human nerve bundles shows bright staining of axons
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.