AMPK has been implicated as a suppressor of cell proliferation of both normal and malignant cells, and recent studies have shown that the binding of AMPK to the PS domain of ULK1, is essential for ULK1-mediated autophagy, and that the phosphorylation of raptor by AMPK, plays an important role in autophagy induction.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:16,000 Western Blot: 1.0-3.0ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:Recognizes human PRKAA2.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to CPLDALNTTKP of human PRKAA2. Species sequence homology: Mouse, rat, canine, porcine and bovine.