TCL1B is a monomeric,15kD (predicted) member of the TCL1 family of proteins.
It is expressed in the embryo and syncytiotrophoblast, and interacts with Akt1 and Akt2 kinase, promoting their activation and the subsequent deactivation of proapoptotic molecules.
Human TCL1B is 128aa in length.
There is no definitive structural motif that characterizes TCL1B, save for a unique b-barrel configuration.
Full length human TCL1B shares less than 35aa identity with five orthologous mouse TCL1B isoforms.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 5-15ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 200ug/ml.
Specificity:Recognizes human TCL1B. Species sequence homology: recombinant human TCL1A (5%).
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Recombinant corresponding to aa2-128 (aa93) from human TCL1B expressed in E. coli (O95988).