84-1196-13　Rab25 100ug　R0009-83B

特徴

• Ras-related protein Rab25, is a 23kD (unglycosylated) member of the small GTPase superfamily and Rab family of proteins.
• Human Rab25 is 213aa in length.
• The mature chain runs from aa1-210 with residues 211-213 constituting a propeptide.
• Residues 10-174 are noted to be Rab11-like.
• Rab11a, Rab11b, and Rab25 are closely related Rab proteins that are differentially expressed.
• Human Rab25 shares 96aa sequence identity with mouse Rab25.
• Functionally, Rab25 is involved in the regulation of cell survival.
• Researchers have shown that Rab25 promotes invasive migration of cells and increases the rates and aggressiveness of breast and ovarian cancers.
• It is expressed in breast and ovarian tissues.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 2ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.