Pancreatic polypeptide (PP) is an 4kD, unglycosylated member of the Neuropeptide-Y family of secreted peptide hormones.
Human PP is synthesized with a 29aa signal sequence and a 66aa prohormone that contains the 36aa PP hormone, a 20aa icosapeptide of unknown function, and a C-terminal prosequence.
PP is produced by pancreatic islet F-cells and released to the circulation following a meal.
It slows stomach emptying time and insulin secretion and is thought to inhibit further food intake.
The human PP prohormone shares 57-55aa identity with mouse and rat PP, respectively.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 5-15ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 200ug/ml.
Specificity：Recognizes human Pancreatic Polypeptide.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic polypeptide corresponding to aa30-95 from human Pancreatic Polypeptide/PP (P01298).
