84-1195-90　Lipoprotein Receptor-related Protein 5, Low Density (LRP5, BMND1, HBM, HGNC:6697, LR3, LRP7, Osteoporosis Pseudoglioma Syndrome, OPPG, OPS, VBCH2) 100ug　L2601-05Z1

特徴

• LRP-5 (low-density lipoprotein receptor-related protein 5) is a 1615aa, 180-200kD type I transmembrane glycoprotein.
• The 1353aa extracellular domain (ECD) contains 20 class B LDLR, 4 EGF-like, and 3 class A LDLR repeats.
• Human LRP-5aa 745-1097 encompasses class B LDLR repeats #12-17 and EGF-like repeat #3.
• It shares 94aa identity with mouse and rat LRP-5, and 70aa identity with human LRP-6 within corresponding regions.
• LRP-5 and LRP-6 mediate DKK effects on Wnt signaling.
• LRP-5 polymorphisms correlate with susceptibility and resistance to osteoporosis.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.