Gastrokine 1 is an 18kD member of the CA11 protein family.
It has limited expression, being restricted to mucous secreting pyloric atrial epithelium.
Gastrokine 1 appears to promote epithelial proliferation and migration, and induce the formation of tight junctions between epithelial cells.
Mature human Gastrokine 1 is 165aa in length.
Based on the SwissProt sequence, it possesses one BRICHOS domain aa54-150 that contains a mitogenic sequence aa97-117.
There is one potential alternative start site 14 aa upstream of the standard site that does not appear to be utilized.
Over aa21-185 (aa35-199 of SwissProt Q9NS71), human Gastrokine 1 shares 65aa identity with mouse Gastrokine 1.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：sheep
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 200ug/ml.
Specificity：Recognizes human Gastrokine 1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Recombinant corresponding to aa35-199 from human Gastrokine 1 expressed in E. Coli (Q9NS71). Species sequence homology: Recombinant mouse Gastrokine 1 (3%).
