84-1195-21 Zic2 (Zinc Finger Protein of the Cerebellum 2, HPE5, Zic 2, Zic Family Member 2 (Odd-paired Drosophila Homolog), Zinc Finger Protein Zic2, Zinc Finger Protein Zic-2) 100ug Z0422-01C
84-1195-21 Zic2 (Zinc Finger Protein of the Cerebellum 2, HPE5, Zic 2, Zic Family Member 2 (Odd-paired Drosophila Homolog), Zinc Finger Protein Zic2, Zinc Finger Protein Zic-2) 100ug Z0422-01C
Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family.
This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1.
Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects.
Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 4-7ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:HepG2 call lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:Recognizes human ZIC2. Species Crossreactivity: chicken, chimpanzee, bovine, canine, equine, monkey, mouse.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Bo Ca Ch Eq Hu Mk Mo
Immunogen:Synthetic peptide corresponding to aa50 to 400 of human ZIC2.