TLR13, also known as Toll like receptor 13, is a member of the Toll-like receptor (TLR) family of transmembrane proteins comprised of multiple copies of leucine rich repeats in the extracellular domain and a TIR domain.
The exact function of this 991aa containing protein is yet unknown, but reports suggest that it is closely related to TLR3 and participates in the innate immune response to microbial agents.
TLR13 binds to and acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and inflammatory response.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1-3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity：Recognizes mouse TLR13. Species Crossreactivity: rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo Rt
Immunogen：Synthetic peptide corresponding to aa800 to 850 of mouse TLR13.
