RGS19 is a member of the RGS protein family, which acts as a GTPase-activating protein (GAPs) for heterotrimeric G proteins, increasing the intrinsic rate of GTP hydrolysis and accelerating signal termination.
It is a small protein that contains two potential phosphorylation sites for protein kinase C and seven for casein kinase 2.
The gene for RGS19 is localized on human chromosome 20q13.33.
RGS19 specifically controls signaling of the Wnt-catenin pathway.
The protein is highly expressed in human lung, liver, heart and placenta.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry (formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Ramos, mouse placenta lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity：Recognizes human RGS19. Species Crossreactivity: mouse. Species sequence homology: bovine, rat.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa1-50 of human RGS19.
