NIBP is a 1246aa intracellular regulatory protein.
Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway.
Due to its neuronal expression NIBP is considered as a potential target for modulating the NF-(kappa) B signaling cascade in neuronal pathologies dependent upon abnormal activation of this pathway.
NIBP is mainly expressed in brain, muscle, heart, and kidney.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunocytochemistry and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity：Recognizes human NIBP. Species Crossreactivity: bovine, chicken, chimpanzee, canine, monkey, mouse. Species sequence homology: xenopus.
Isotype：IgG
Calc Applications Abbrev：IC IF IP WB
Calc Crossreactivity：Bo Ca Ch Hu Mk Mo
Immunogen：Synthetic peptide corresponding to aa282-299 (KKDFVGLDTDSRHYKKRC) of human NIBP.
