84-1193-29　NFATC1 (Nuclear Factor of Activated T-cells, Cytoplasmic 1, NF-ATc1, NFATc1, NFAT Transcription Complex Cytosolic Component, NF-ATc, NFATc, NFAT2, NFATC) 100ug　N2375-10D

特徴

• NFAT (nuclear factor of activated T cell transcription factors play critical roles in gene transcription during immune responses.
• The NFAT complex is made up of NFATc (NFATc1-4) protein and activator protein-1 (AP-1) transcription factor.
• NFAT proteins are regulated by Ca2+.
• NFATc1 is a substrate protein phosphatase calcineurin, a critical mediator of calcium signals during T-cell activation.
• NFATc1 activation requires the translocation of the transcription factor into the nucleus, a process that is mediated by calcineurin.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1-3ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Ramos cell lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.