NPFF2, a 60kD transmembrane protein, is a G-protein coupled NPFF receptor & shares homology with the seven trans-membrane domain receptor super family.
It has a tissue-restricted distribution and consists of a 147-residue-N-terminal domain, 7 transmembrane domains and a C-terminal domain.
It binds NPFF and might play a role in pain modulation and opiate tolerance.
Reports suggest NPFF2 binds Prolactin releasing peptide and mediates its signaling.
Northern Blot analysis detected a high expression of NPFF2 transcript in placenta, testis, thymus and small intestine with a moderate expression in other tissues.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Recognizes human NPFF2. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa405-420 (ELVMEELKETTNSSEI) of human NPFF2
