Mip1 is a novel member of a group of highly conserved proteins.
Originally identified as a RAS suppressor protein, Mip1 is a human ortholog of S.
cerevisiae Sin1.
Studies reveal that Mip1 interacts with proteins involved in MAPK signaling including MEKK2 and participates in the regulation of MEKK2 activation and signaling.
It also has been found to bind to JNK and might act as a scaffold molecule in the regulation of JNK signaling.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Human heart or skeletal muscle cell lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity Chromatography.
Form：Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Specificity：Recognizes human Mapkap1. Species Crossreactivity: avian, bovine, chicken, canine, mouse, rat, zebrafish.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Av Bo Ca Ch Hu Mo Rt Ze
Immunogen：Synthetic peptide corresponding to aa85-102 (NTAQRLERLRKERQNQIK) of human Mip1.
