84-1192-93　MAGED2 (Melanoma-associated Antigen D2, MAGE-D2 Antigen, Breast Cancer-associated Gene 1 Protein, BCG-1, 11B6, Hepatocellular Carcinoma-associated Protein JCL-1, BCG1) 100ug　M1750-05E

特徴

• MAGE-D2, also known as Melanoma-associated antigen D2, belongs to the melanoma antigen encoding gene (MAGE) family with a MAGE domain.
• Rat and mouse orthologues have been isolated.
• Compared to other proteins (MAGE-A, MAGE- B and MAGE-C clusters) MAGE-D2 is expressed ubiquitously.
• This intracellular protein shows high expression in specific brain regions and in the interstitium of testes.
• Though the exact function of this protein is yet to be deduced, MAGE-D2 is considered as a hot spot for X-linked mental retardation.
• Research reveals that MAGE-D2 might have some role in breast and gastric cancer, as well as in hepatocellular carcinoma.
• MAGE-D2 is also known to interact physically with p53 and modify its activity, thus acting as a p53-dissociator.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 5-7ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.