Homeobox protein HB9 is expressed in lymphoid and pancreatic tissues.
It is reported to be Putative transcription factor involved in pancreas development and function.
Defects in this gene causes Currarino syndrome.
The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development.
It is also reported that HB9 is strongly expressed in epidermal basal cells of the outer scale face in tarsometatarsal scale skin.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlImmunohistochemistry (formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:Recognizes mouse HB9. Species Crossreactivity: human, rat. Species sequence homology: canine, opossum.
Isotype:IgG
Calc Applications Abbrev:IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to aa330-380 of mouse HB9.