84-1192-55 HMG4 (High Mobility Group 4 (HMG) Transcription Factor, High Mobility Group Protein 2a, HMG2a, High Mobility Group Box 3, HMGB3, MGC90319, Nonhistone Chromosomal Protein HMG4) 100ug H6202-41B
84-1192-55 HMG4 (High Mobility Group 4 (HMG) Transcription Factor, High Mobility Group Protein 2a, HMG2a, High Mobility Group Box 3, HMGB3, MGC90319, Nonhistone Chromosomal Protein HMG4) 100ug H6202-41B
HMGB3, also known as High mobility group protein B3, is a DNA associated protein that binds preferentially single-stranded DNA and unwinds double stranded DNA.
This transcription factor belongs to the HMGB family and high mobility group (HMG) protein superfamily and contains two HMG box DNA-binding domains.
Like other members of the family, HMGB3 plays a fundamental role in DNA replication, nucleosome assembly and transcription.
Other functions include regulation of balance between hematopoietic stem cell self-renewal and differentiation and may also be required during embryonic development.
HMGB3 is predominantly expressed in placenta.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Mouse placenta
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:Recognizes human HMGB3. Species Crossreactivity: chicken, chimpanzee, bovine, canine, equine, mouse.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Bo Ca Ch Eq Hu Mo
Immunogen: Synthetic peptide corresponding to aa150-200 of human HMGB3.