84-1192-37　LGR7 (Relaxin Receptor 1, Leucine-rich Repeat-containing G-protein Coupled Receptor 7, Relaxin Family Peptide Receptor 1, RXFP1) 100ul　G8602-75C

特徴

• The relaxin receptor, LRG7, has recently been identified as the only human G-protein-coupled receptor to contain a low-density lipoprotein class-A (LDL-A) module.
• The mosaic protein contains an N-terminal low density lipoprotein (LDL) receptor cysteine-rich motif, a set of ten leucine-rich repeats and a seven transmembrane region with an intracellular C-terminus.
• The protein specifically binds human relaxins H1 and H2 with high affinity and thus stimulates adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes.
• LGR7 is critical for mediating these biological responses by use of RNA interference lentiviral short hairpin constructs.
• The gene encoding for LRG7 is mapped to 4q32.1 region of human chromosome.
• The protein is commonly expressed in human brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart.
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry (formalin fixed paraffin embedded): 1:100Immunohistochemistry: frozenOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.