CD97 is a monomeric glycoprotein belonging to G-protein coupled receptor 2 family and having a seven-span transmembrane region homologous to the secretin receptor super family.
It is usually induced on the surface of activated leukocytes and has four tandem EGF-like domains two of them have calcium binding sites and a single RGD motif and several potential N and O glycosylation sites.
It is known to act as a receptor that is not only involved in adhesion but also takes part in signaling processes early after leukocyte activation and also has a cellular ligand CD55 CD55, DAF.
Over expression of this protein may sometimes lead to gastrointestinal carcinomas.
CD97 an epidermal growth factor (EGF)-TM7 receptor is expressed on smooth muscle cells and other cells of the immune system.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 3-5ug/mlImmunohistochemistry (paraffin): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Specificity：Recognizes human CD97. Species Crossreactivity: chimpanzee, mouse. Species sequence homology: monkey.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to aa220-270 of human Leukocyte Antigen CD97.
