84-1190-93 Bacillus anthracis PA (Protective Antigen) 100ul B0003-08D9
特徴
- Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis.
- All three of the proteins must be present for toxic entry into cells.
- PA is secreted from Bacillus anthracis as an 83kD (PA83) protein which is cleaved by furin protease, releasing a 20kD fragment.
- The 63kD portion (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF.
- This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
- Positive Control:PA recombinant protein
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Grade：Serum
- Purity：Serum.
- Form：Supplied as a liquid in PBS. No preservative added.
- Specificity：Recognizes Anthrax PA protein.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Immunogen：Synthetic peptide corresponding to aa240-254 of the Anthrax PA protein (~83kD).
- Shelf Life：1year
- EU Commodity Code：30021010
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