AROS, a nucleolar protein with an unknown function, interacts with extraribosomal protein RPS19, playing a role in the signaling pathways that regulate rRNA transcription.
The deduced aa sequence of AROS, derived from cDNA, defines an isoelectric point of 11.3.
No known functional motifs were found in AROS except a short polylysine tract embedded in a putative nucleolar localization signal.
At a basal level the protein is expressed ubiquitously with a significantly high level of expression in some tissues.
Human AROS gene is mapped to chromosome 22q13.1.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 2-4ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Human liver
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
Specificity:Recognizes human AROS.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa1-50 of human AROS.