Lymphocyte-specific protein-tyrosine kinase (Lck), also known as p56Lck and Lsk, is a member of the Src family of non-receptor tyrosine kinases.
First identified as a gene rearranged and overexpressed in murine lymphomas, lck behaves as a proto-oncogene and its activation can lead to cellular transformation.
Lck protein is anchored to the plasma membrane and interacts with the intracellular domains of CD4/CD8 co-receptors in T lymphocytes.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS with 5% trehalose. Reconstitute with sterile PBS.
Specificity：Recognizes human Lck.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Recombinant corresponding to aa1-66 from human Lck expressed in E. coli (P06239).
