Angiopoietin-like Factor (ANGPTL7), also known as cornea-derived transcript 6 (CDT6), is a secreted 45kD protein that contains a coiled-coil domain (aa30-110) and a fibrinogen-like domain (aa113-334).
ANGPTL7 is expressed in the stromal layer of the cornea, and it forms disulfide-linked homotetramers.
It contributes to corneal morphogenesis by suppressing angiogenesis and promoting the deposition of extracellular matrix components.
ANGPTL7 is up-regulated in glaucoma and accumulates in the aqueous humor.
Mature mouse ANGPTL7 shares 88% and 98% sequence identity with human and rat ANGPTL7.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Direct ELISA: 0.5-1ug/mlWestern Blot: 1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS.
Specificity：Recognizes mouse ANGPTL7.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Mo
Immunogen：Recombinant corresponding to mouse ANGPTL7 expressed in NSO cells (Q8R1Q3).
