Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF) is widely distributed throughout the body.
It has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids.
Somatostatin is an important regulator of endocrine and nervous system function.
It exerts its biologic actions by binding to specific high affinity receptors on the cell surface.
Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid.
Applications:Suitable for use in Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilutions:Immunofluorescence: 1:200Immunohistochemistry (PAP or ABC): 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Serum
Purity:Serum.
Form:Supplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O.
Specificity:Recognizes human Somatostatin. Species Crossreactivity: rat, mouse and porcine. Crossreactivity: Somatostatin-25, 100%. Sequence Homology: Somatostatin-28; 55.7%, Pro-Somatostatin (1-32)/N-Terminal Pepro-Somatostatin (porcine); 0.002%, human Insulin, human Glucagon, human Amylin, Substance P (human, rat, mouse), VIP (human, mouse, porcine, rat, sheep); 0%.
Isotype:IgG
Calc Applications Abbrev:IF IHC
Calc Crossreactivity:Hu Mo Po Rt
Immunogen:Synthetic peptide corresponding to human Somatostatin.