GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus.
The preproprotein is cleaved to form a 44 amino acid factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary.
Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors.
Defects in this protein are a cause of dwarfism, while hypersecretion of the protein is a cause of gigantism.
Applications:Suitable for use in Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry (PAP or ABC): 1:500Immunofluorescence: 1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months after receipt at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 50ul sterile ddH2O.
Specificity：Recognizes human GHRF. Species Crossreactivity: bovine, porcine, sheep, rat, GHRF - 100%; human GHRF (aa1-40) - 100%; human GHRF (aa1-37) - 80%; human, porcine, rat VIP - 0%; human Growth Hormone - 0%; human Secretin - 0%; human GIP - 0%.
Isotype：IgG
Calc Applications Abbrev：IF IHC
Calc Crossreactivity：Bo Hu Po Rt Sh
Immunogen：Synthetic peptide corresponding to human GHRF.
