a1-Antichymotrypsin (AACT, Alpha1-ACT) is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
a1-Antichymotrypsin, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer’s disease (AD) and in normal-aged human and monkey brain.
Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to a1-Antichymotrypsin.
A higher proportion of serum PSA is complexed to a1-Antichymotrypsin in prostate cancer than in benign prostate hyperplasia.
Applications:Suitable for use in ELISA, Immunoprecipitation, Immunodiffusion, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1mg
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography. ≥ 95% (SDS-PAGE).
Form：Supplied as a liquid in 10mM sodium phosphate, 0.15M sodium chloride, pH 7.2, 0.05% sodium azide.
Specificity：Recognizes human alpha1-Antichymotrypsin.
