Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters.
Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-13, Mol.
Wt.
40-80kD) and Sodium glucose co-transporter-1 (SGLT-1, 662aa; ~75kD).
Individual member of this family have identical predicted secondary structures with 12 transmembrane domains.
Both N and C-termini are predicted to be cytoplasmic.
Most differences in sequence homology exist within the four hydrophilic domains that may play a role in tissue-specific targeting.
Glut isoform differ in their tissue expression, substrate specificity and kinetic characteristics.
Applications:Suitable for use in Western Blot and ELISA.
Control peptide can be used to coat ELISA plates at 1ug/ml Optimal dilutions to be determined by the researcher.
Control Peptide:G3900-80J: GLUT7, Control Peptide (Solute Carrier Family 2, Facilitated Glucose Transporter Member 7, Glucose Transporter Type 7, GLUT-7, SLC2A7)Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
Specificity:Recognizes human GLUT7.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 12aa near the C-terminal, cytoplasmic domain of human GLUT7 conjugated to KLH.