FABPs are small intracellular proteins (~13-14kD) with a high degree of tissue specificity that bind long chain fatty acids.
They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism.
There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression.
Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels.
Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas.
IL-FABP is localized in the intestine, ovary, adrenals and stomach.
Applications:Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Other applications have not been tested.
Recommended Dilutions: Immunohistochemistry (Paraffin): 1:50 Western Blot: 1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Specificity:Recognizes mouse Ileal Fatty Acid Binding Protein of both natural and recombinant origin. Species Crossreactivity: rat.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Mo Rt
Immunogen:Ileal Fatty Acid Binding Protein dervied from the mouse FABP6 gene.