84-1174-52 TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) (Biotin) 50ug T8250-31B
84-1174-52 TGFBR1, ID (TGF-beta Receptor Type I, TGFR-1, Transforming Growth Factor-beta Receptor Type I, TGF-beta Type I Receptor, TbetaR-I, TGF-beta Type I Receptor, Activin Receptor-like Kinase 5, ALK-5, TGF beta Receptor I) (Biotin) 50ug T8250-31B
TGF-b RI, also known as activin-like kinase 5 (ALK-5), is a 55kD type I transmembrane serine/threonine receptor kinase.
It is ubiquitously expressed and forms a functional heterotetrameric signaling TGF-b receptor complex with TGF-b RII.
The aa sequence of human TGF-b RI extracellular domain is 91%, 90%, 91% and 93% identical to that of porcine, mouse, bovine and rat TGF-b RI, respectively.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.1-0.2ug/ml.
The detection limit for hFibronectin is approximately 25ng/lane under non-reducing and reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile TBS, 0.01% BSA.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:50ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 50ug/1ug BSA. Labeled with Biotin. Reconstitute with sterile TBS, pH 7.3, 20mM Trizma, 150mM sodium chloride, 0.1% BSA.
Specificity:Recognizes human TGF-beta RI. Species sequence homology: rat (93%), porcine and bovine (91%), mouse (90%).
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Purified, NS0-derived, recombinant human TGF-b RI.