84-1173-98　［受注停止］Draxin (Dorsal Repulsive Axon Guidance Protein, Neucrin, C1orf187, PSEC0258, UNQ3119/PRO10268) 100ug　D9392-02

特徴

• Draxin (Dorsal repulsive axon guidance protein; also neucrin) is a secreted, 58kD, presumable glycoprotein member of the draxin family of molecules.
• In mammals, it is expressed in neurons (axons), astroglia, and likely cells of the developing somite.
• Draxin acts as a Wnt antagonist, apparently by binding to LRP6.
• The net effect is to block neural crest migration, and the organization of axons into functional tracts or bundles (fasciculation).
• Mature human Draxin is 324aa in length.
• It contains one potential N-linked glycosylation site, followed by a Cys-rich domain (aa274-333).
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 1ug/mlELISA: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.