c-Rel is the cellular cognate of v-Rel, the avian reticuloendo-theliosis virus strain T transforming gene.
V-Rel encodes a 59kDa phosphoprotein that is located in the cytoplasm of transformed spleen cells and in the nucleus of non transformed fibroblasts, in contrast to the c-Rel protein which is cytoplasmic.
C-Rel was shown to represent a constituent of the kB site binding transcription factor NFkB, which plays a crucial role in the expression of immunoglobulin k light chain gene.
Applications:Suitable for use in Immunofluorescence Other applications not tested.
Recommended Dilution:Immunofluorescence:1:100-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human Rel.
Isotype：IgG
Calc Applications Abbrev：IF
Calc Crossreactivity：Hu
Immunogen：Synthetic non-phosphopeptide corresponding to human Rel around the phosphorylation site of serine 503 (T-S-SP-D-S).
