OPCML is a member of the IgLON family of immunoglobulin (Ig)domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC.
The OPCML gene comprises 7 exons,spans approximately 600kb, and is transcribed from telomere to centromere .
And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.
Applications:Suitable for use in Western Blot and Immunohistochemistry.