84-1168-06　CD22 (B Cell Receptor CD22, B-lymphocyte Cell Adhesion Molecule, BL-CAM, T-cell Surface Antigen Leu-14, MGC130020, Sialic Acid Binding Immunoglobulin-like Lectin 2, Sialic Acid-binding Ig-like Lectin 2, Siglec 2, Siglec 2, Siglec 2) 100ug　C2272-98H

特徴

• CD22 is a surface glycoprotein of B lymphocytes that is rapidly phosphorylated on cytoplasmic tyrosines after antigen receptor cross-linking.
• CD22 is a negative regulator of antigen receptor signaling whose onset of expression at the mature B cell stage may serve to raise the antigen concentration threshold required for B cell triggering.
• The human CD22 gene is expressed specifically in B lymphocytes and likely has an important function in cell-cell interactions.
• The B cell coreceptor CD22 plays an important role in regulating signal transduction via the B cell Ag receptor.
• CD22 is located within the band region q13.1 of chromosome 19.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 0.5-1ug/ml detects CD22 in cells and tissues
• Immunohistochemistry (FFPE) : 0.5-1ug/ml detects CD22 in formalin fixed paraffin-embedded tissues
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.