The protein encoded by this gene is involved in the conversion of tyrosine to dopamine.
It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons.
Mutations in this gene have been associated with autosomal recessive Segawa syndrome.
Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Applications:Suitable for use in ELISA and Western Blot.
Other applications have not been tested.
Recommended Dilutions: Peptide ELISA Titer: 1:8000Western Blot: 2-4ug/ml ~55kD band observed in Human Brain (Cerebral Cortex) lysates (calculated MW of 55.5kD according to NP_000351.2)Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide affinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human Tyrosine Hydroxylase. This antibody is expected to recognise all three reported isoforms (as represented by NP_954986.2; NP_000351.2; NP_954987.2). Species sequence homology: rat, canine.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-VQDELDTLAHAL, from the C Terminus of human Tyrosine Hydroxylase (NP_954986.2; NP_000351.2; NP_954987.2).
