This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain.
The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores.
This ubiquitously expressed gene has elevated expression in liver and kidney.
Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions: Peptide ELISA Titer: 1:16,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide affinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes TPCN2. Species sequence homology: human.
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-EDELTERLSQHPH, from the C-Terminus of human TPCN2 (NP_620714.2).
