This gene encodes a member of the sorting nexin family.
Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking.
This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor.
This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes.
This protein may form oligomeric complexes with family members.
This gene results in three transcript variants encoding distinct isoforms.
Applications:Suitable for use in ELISA and Western Blot.
Other applications have not been tested.
Recommended Dilutions: Peptide ELISA Titer: 1:64,000Western Blot: 1-3ug/ml ~75kD band observed in Human lysates of cell line HeLa (calculated MW of 59.1kD according to NP_003090.2).
The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources.
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide affinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human SNX1. Species sequence homology: mouse, rat, canine, bovine. This antibody is expected to recognize isoform a and c (NP_003090.2; NP_690039.1).
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-TNSSKPQPTYEELE, from the internal region of human SNX1 (NP_003090.2; NP_690039.1).
