This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily.
The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins.
The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome.
The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system.
Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.
Applications:Suitable for use in ELISA.
Other applications have not been tested.
Recommended Dilutions: Peptide ELISA Titer: 1:8000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide affinity chromatography.
Form：Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes PCDH11Y. Species sequence homology: human. This antibody is expected to recognize all reported Y-linked isoforms (NP_116753.1; NP_116754.1; NP_116755.1) and all reported X-linked isoforms (NP_055337.1; NP_055337.1; NP_116750.1; NP_116751.1).
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to C-KYNWVTTPTTFK, from the internal region of human PCDH11Y (NP_116753.1; NP_116754.1; NP_116755.1; NP_055337.1; NP_055337.1; NP_116750.1; NP_116751.1).
